Genome-Wide Analyses of Prognostic and Therapeutic Alternative Splicing Signatures in Bladder Urothelial Carcinoma

Genome-Wide Analyses of Prognostic and Therapeutic Alternative Splicing Signatures in Bladder Urothelial Carcinoma

BackgroundAlternative splicing (AS) is an indispensable post-transcriptional modification applied during the maturation of mRNA, and AS defects have been associated with many cancers. This study was designed to thoroughly analyze AS events in bladder urothelial carcinoma (BLCA) at the genome-wide le...

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Bibliographic Details
Main Authors: Zhongru Fan, Zhe Zhang, Chiyuan Piao, Zhuona Liu, Zeshu Wang, Chuize Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
alternative splicing (AS)
bladder urothelial carcinoma (BLCA)
prognosis signature
regulatory network
splicing factor
immuno/chemotherapies
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.626858/full

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