MYD88, NFKB1, and IL6 transcripts overexpression are associated with poor outcomes and short survival in neonatal sepsis

Abstract Toll-like receptor (TLR) family signature has been implicated in sepsis etiopathology. We aimed to evaluate the genetic profile of TLR pathway-related key genes; the myeloid differentiation protein 88 (MYD88), IL1 receptor-associated kinase 1 (IRAK1), the nuclear factor kappa-B1 (NFKB1), an...

Full description

Bibliographic Details
Main Authors: Nouran B. AbdAllah, Eman A. Toraih, Essam Al Ageeli, Hala Elhagrasy, Nawal S. Gouda, Manal S. Fawzy, Ghada M. Helal
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92912-7