Cre-assisted fine-mapping of neural circuits using orthogonal split inteins

Existing genetic methods of neuronal targeting do not routinely achieve the resolution required for mapping brain circuits. New approaches are thus necessary. Here, we introduce a method for refined neuronal targeting that can be applied iteratively. Restriction achieved at the first step can be fur...

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Bibliographic Details
Main Authors: Haojiang Luan, Alexander Kuzin, Ward F Odenwald, Benjamin H White
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/53041