Rubiacordone A: A New Anthraquinone Glycoside from the Roots of Rubia cordifolia

Rubiacordone A: A New Anthraquinone Glycoside from the Roots of Rubia cordifolia

A new anthraquinone, Rubiacordone A (1) (6-acetoxy-1-hydroxy-2-methylanthraquinone-3-O-α-L-rhamnopyranoside), was isolated together with the known anthraquinone, 1-acetoxy-6-hydroxy-2-methylanthraquinone-3-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside] (2), from the dried roots of R...

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Bibliographic Details
Main Authors: Xiang Li, Zhi Liu, Yun Chen, Chang-Chun Ruan, Li-Juan Wang, Yi-Nan Zheng, Guang-Zhi Sun
Format: Article
Language:English
Published: MDPI AG 2009-01-01
Series:Molecules
Subjects:
Rubia cordifolia
Rubiacordone A
Anthraquinone
Antimicrobial
Online Access:http://www.mdpi.com/1420-3049/14/1/566/
Description
Summary:A new anthraquinone, Rubiacordone A (1) (6-acetoxy-1-hydroxy-2-methylanthraquinone-3-O-α-L-rhamnopyranoside), was isolated together with the known anthraquinone, 1-acetoxy-6-hydroxy-2-methylanthraquinone-3-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside] (2), from the dried roots of Rubia cordifolia. Their structures were elucidated on the basis of extensive 1D and 2D-NMR, as well as HRESI-MS spectroscopic analysis. Metabolites 1 and 2 showed considerable antimicrobial activity against Gram-positive bacteria.
ISSN:1420-3049

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