Multi-scale modeling of the circadian modulation of learning and memory.

We propose a multi-scale model to explain the time-of-day effects on learning and memory. We specifically model the circadian variation of hippocampus (HC) dependent long-term potentiation (LTP), depression (LTD), and the fear conditioning paradigm in amygdala. The model we built has both Goodwin ty...

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Bibliographic Details
Main Authors: Shiju S, K Sriram
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0219915