Biomedical Application of Functional Materials in Organ-on-a-Chip

The organ-on-a-chip (OOC) technology has been utilized in a lot of biomedical fields such as fundamental physiological and pharmacological researches. Various materials have been introduced in OOC and can be broadly classified into inorganic, organic, and hybrid materials. Although PDMS continues to...

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Main Authors:	Chizhu Ding, Xiang Chen, Qinshu Kang, Xianghua Yan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-07-01
Series:	Frontiers in Bioengineering and Biotechnology
Subjects:	organ-on-a-chip microfluidics elastomer hydrogel microfabrication
Online Access:	https://www.frontiersin.org/article/10.3389/fbioe.2020.00823/full

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record_format	Article
spelling	doaj-cb83cac0efc6460886374db6803fef1a2020-11-25T03:28:52ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852020-07-01810.3389/fbioe.2020.00823555817Biomedical Application of Functional Materials in Organ-on-a-ChipChizhu Ding0Xiang Chen1Qinshu Kang2Xianghua Yan3Xianghua Yan4Xianghua Yan5State Key Laboratory of Agricultural Microbiology, College of Science, Huazhong Agricultural University, Wuhan, ChinaState Key Laboratory of Agricultural Microbiology, College of Science, Huazhong Agricultural University, Wuhan, ChinaState Key Laboratory of Agricultural Microbiology, College of Science, Huazhong Agricultural University, Wuhan, ChinaState Key Laboratory of Agricultural Microbiology, College of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, ChinaThe Cooperative Innovation Center for Sustainable Pig Production, Wuhan, ChinaHubei Provincial Engineering Laboratory for Pig Precision Feeding and Feed Safety Technology, Wuhan, ChinaThe organ-on-a-chip (OOC) technology has been utilized in a lot of biomedical fields such as fundamental physiological and pharmacological researches. Various materials have been introduced in OOC and can be broadly classified into inorganic, organic, and hybrid materials. Although PDMS continues to be the preferred material for laboratory research, materials for OOC are constantly evolving and progressing, and have promoted the development of OOC. This mini review provides a summary of the various type of materials for OOC systems, focusing on the progress of materials and related fabrication technologies within the last 5 years. The advantages and drawbacks of these materials in particular applications are discussed. In addition, future perspectives and challenges are also discussed.https://www.frontiersin.org/article/10.3389/fbioe.2020.00823/fullorgan-on-a-chipmicrofluidicselastomerhydrogelmicrofabrication
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Chizhu Ding Xiang Chen Qinshu Kang Xianghua Yan Xianghua Yan Xianghua Yan
spellingShingle	Chizhu Ding Xiang Chen Qinshu Kang Xianghua Yan Xianghua Yan Xianghua Yan Biomedical Application of Functional Materials in Organ-on-a-Chip Frontiers in Bioengineering and Biotechnology organ-on-a-chip microfluidics elastomer hydrogel microfabrication
author_facet	Chizhu Ding Xiang Chen Qinshu Kang Xianghua Yan Xianghua Yan Xianghua Yan
author_sort	Chizhu Ding
title	Biomedical Application of Functional Materials in Organ-on-a-Chip
title_short	Biomedical Application of Functional Materials in Organ-on-a-Chip
title_full	Biomedical Application of Functional Materials in Organ-on-a-Chip
title_fullStr	Biomedical Application of Functional Materials in Organ-on-a-Chip
title_full_unstemmed	Biomedical Application of Functional Materials in Organ-on-a-Chip
title_sort	biomedical application of functional materials in organ-on-a-chip
publisher	Frontiers Media S.A.
series	Frontiers in Bioengineering and Biotechnology
issn	2296-4185
publishDate	2020-07-01
description	The organ-on-a-chip (OOC) technology has been utilized in a lot of biomedical fields such as fundamental physiological and pharmacological researches. Various materials have been introduced in OOC and can be broadly classified into inorganic, organic, and hybrid materials. Although PDMS continues to be the preferred material for laboratory research, materials for OOC are constantly evolving and progressing, and have promoted the development of OOC. This mini review provides a summary of the various type of materials for OOC systems, focusing on the progress of materials and related fabrication technologies within the last 5 years. The advantages and drawbacks of these materials in particular applications are discussed. In addition, future perspectives and challenges are also discussed.
topic	organ-on-a-chip microfluidics elastomer hydrogel microfabrication
url	https://www.frontiersin.org/article/10.3389/fbioe.2020.00823/full
work_keys_str_mv	AT chizhuding biomedicalapplicationoffunctionalmaterialsinorganonachip AT xiangchen biomedicalapplicationoffunctionalmaterialsinorganonachip AT qinshukang biomedicalapplicationoffunctionalmaterialsinorganonachip AT xianghuayan biomedicalapplicationoffunctionalmaterialsinorganonachip AT xianghuayan biomedicalapplicationoffunctionalmaterialsinorganonachip AT xianghuayan biomedicalapplicationoffunctionalmaterialsinorganonachip
_version_	1724582283383406592

Biomedical Application of Functional Materials in Organ-on-a-Chip

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