LINC00152 upregulates ZEB1 expression and enhances epithelial-mesenchymal transition and oxaliplatin resistance in esophageal cancer by interacting with EZH2

LINC00152 upregulates ZEB1 expression and enhances epithelial-mesenchymal transition and oxaliplatin resistance in esophageal cancer by interacting with EZH2

Abstract Background Expression of the long non-coding mRNA LINC00152 has been reported to correlate with cancer cell resistance to oxaliplatin (L-OHP). However, little is known regarding the molecular mechanism of LINC00152 in esophageal cancer (EC). Hence, we intended to characterize the role of LI...

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Bibliographic Details
Main Authors: Shuyao Zhang, Wei Liao, Qinshui Wu, Xiaoshan Huang, Zhen Pan, Wang Chen, Shuyi Gu, Zuojun Huang, Yiwen Wang, Xu Tang, Shanshan Liang, Xiaoyan Zhang, Yun Chen, Shuang Chen, Wanying Chen, Yi Jiang, Chen Chen, Guodong Qiu
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Cancer Cell International
Subjects:
Esophageal cancer
LINC00152
Zeste Homologue 2
Zinc finger e-box binding homeobox 1
Epithelial-mesenchymal transition
Chemotherapy resistance
Online Access:http://link.springer.com/article/10.1186/s12935-020-01620-1

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http://link.springer.com/article/10.1186/s12935-020-01620-1

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