Synthesis and Modeling Studies of Furoxan Coupled Spiro-Isoquinolino Piperidine Derivatives as NO Releasing PDE 5 Inhibitors

Synthesis and Modeling Studies of Furoxan Coupled Spiro-Isoquinolino Piperidine Derivatives as NO Releasing PDE 5 Inhibitors

Nitric oxide (NO) is considered to be one of the most important intracellular messengers that play an active role as neurotransmitter in regulation of various cardiovascular physiological and pathological processes. Nitric oxide (NO) is a major factor in penile erectile function. NO exerts a relaxin...

Full description

Bibliographic Details
Main Authors: Swami Prabhuling, Yasinalli Tamboli, Prafulla B. Choudhari, Manish S. Bhatia, Tapan Kumar Mohanta, Ahmed Al-Harrasi, Zubaidha K. Pudukulathan
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Biomedicines
Subjects:
nitric oxide
furoxan
PDE 5 inhibitors
spiro-isoquinolino piperidine
Online Access:https://www.mdpi.com/2227-9059/8/5/121

Similar Items

Similar Items