Evaluation of near infrared dyes as markers of P-glycoprotein activity in tumors
Aim: The multidrug resistance protein 1 (MDR1; P-glycoprotein) has been associated with efflux of chemotherapeutic agents from tumor cells and poor patient prognosis. This study evaluated the feasibility of non-invasive, non-radioactive near infrared (NIR( imaging methodology for detection of MDR1 f...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2016-11-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00426/full |