Role of Epstein–Barr Virus in the Pathogenesis of Head and Neck Cancers and Its Potential as an Immunotherapeutic Target

Role of Epstein–Barr Virus in the Pathogenesis of Head and Neck Cancers and Its Potential as an Immunotherapeutic Target

The role of Epstein–Barr virus (EBV) infection in the development and progression of tumor cells has been described in various cancers. Etiologically, EBV is a causative agent in certain variants of head and neck cancers such as nasopharyngeal cancer. Proteins expressed by the EVB genome are involve...

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Bibliographic Details
Main Authors: Queenie Fernandes, Maysaloun Merhi, Afsheen Raza, Varghese Philipose Inchakalody, Nassima Abdelouahab, Abdul Rehman Zar Gul, Shahab Uddin, Said Dermime
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Oncology
Subjects:
Epstein–Barr virus
head and neck cancers
nasopharyngeal cancer
EBV-induced nuclear antigen 1
LMP
cancer vaccine
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00257/full

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