Drug Efflux Transporters Are Overexpressed in Short-Term Tamoxifen-Induced MCF7 Breast Cancer Cells

Drug Efflux Transporters Are Overexpressed in Short-Term Tamoxifen-Induced MCF7 Breast Cancer Cells

Tamoxifen is the first line drug used in the treatment of estrogen receptor-positive (ER+) breast cancer. The development of multidrug resistance (MDR) to tamoxifen remains a major challenge in the treatment of cancer. One of the mechanisms related to MDR is decrease of drug influx via overexpressio...

Full description

Bibliographic Details
Main Authors:	Desak Gede Budi Krisnamurti, Melva Louisa, Erlia Anggraeni, Septelia Inawati Wanandi
Format:	Article
Language:	English
Published:	Hindawi Limited 2016-01-01
Series:	Advances in Pharmacological Sciences
Online Access:	http://dx.doi.org/10.1155/2016/6702424

Similar Items

Kurkumin Meningkatkan Sensitivitas Sel Kanker Payudara terhadap Tamoksifen Melalui Penghambatan Ekspresi P-glikoprotein dan Breast Cancer Resistance Protein
by: Erlia Anggrainy Sianipar, et al.
Published: (2018-04-01)

Differential expression of several drug transporter genes in HepG2 and Huh-7 cell lines
by: Melva Louisa, et al.
Published: (2016-01-01)

Effect of Allicin on Tamoxifen-sensitive MCF-7 Breast Cancer Cells
by: P Rahimi-Moghaddam, et al.
Published: (2015-05-01)

Simvastatin Evokes An Unpredicted Antagonism For Tamoxifen In MCF-7 Breast Cancer Cells
by: Ibrahim AB, et al.
Published: (2019-11-01)

The Effect of Alpha Mangostin on Epithelial-Mesenchymal Transition on Human Hepatocellular Carcinoma HepG2 Cells Surviving Sorafenib via TGF-β/Smad Pathways
by: Syarinta Adenina, et al.
Published: (2020-08-01)

Differential response to α-oxoaldehydes in tamoxifen resistant MCF-7 breast cancer cells.
by: Norbert Nass, et al.
Published: (2014-01-01)

Correction: Differential Response to α-Oxoaldehydes in Tamoxifen Resistant MCF-7 Breast Cancer Cells
by: The Staff
Published: (2014-01-01)

Correction: Differential Response to α-Oxoaldehydes in Tamoxifen Resistant MCF-7 Breast Cancer Cells.
Published: (2014-01-01)

In Vitro and In Vivo Effects of Xanthorrhizol on Human Breast Cancer MCF-7 Cells Treated With Tamoxifen
by: Nattanant Noomhorm, et al.
Published: (2014-01-01)

Modulation of Tamoxifen Cytotoxicity by Caffeic Acid Phenethyl Ester in MCF-7 Breast Cancer Cells
by: Tarek K. Motawi, et al.
Published: (2016-01-01)

Effect of O-GlcNAcylation on tamoxifen sensitivity in breast cancer derived MCF-7 cells
by: Kanwal, Shahzina
Published: (2013)

In vitro and In vivo Effects of Xanthorrhizol on Human Breast Cancer MCF‐7 cells Treated with Tamoxifen
by: Nattanant Noomhorm, et al.
Published: (2013)

Effect of O-GlcNAcylation on tamoxifen sensitivity in breast cancer derived MCF-7 cells
by: Kanwal, Shahzina
Published: (2013)

Increased vimentin mRNA expression in MCF-7 breast cancer cell line after repeated endoxifen-treatment
by: Paramita Paramita, et al.
Published: (2017-01-01)

Overexpression of CD44 accompanies acquired tamoxifen resistance in MCF7 cells and augments their sensitivity to the stromal factors, heregulin and hyaluronan
by: Hiscox Stephen, et al.
Published: (2012-10-01)

Anti-apoptotic effect of claudin-1 in tamoxifen-treated human breast cancer MCF-7 cells
by: Liu Yang, et al.
Published: (2010-10-01)

Proteomics of sub-cellular protein distribution in oestrogen and tamoxifen stimulated MCF-7 breast cancer cells
by: Alkhanjaf, A. A. M.
Published: (2016)

CHANGES IN DNA METHYLATION PROFILE IN TAMOXIFEN-RESISTANT MCF-7 SUBLINES
by: О. Е. Andreeva, et al.
Published: (2019-11-01)

In silico and in vitro studies on the anti-cancer activity of andrographolide targeting survivin in human breast cancer stem cells.
by: Septelia Inawati Wanandi, et al.
Published: (2020-01-01)

Correction: In silico and in vitro studies on the anti-cancer activity of andrographolide targeting survivin in human breast cancer stem cells.
by: Septelia Inawati Wanandi, et al.
Published: (2021-01-01)

Overexpression of ABCC2 and NF-Κβ/p65 with Reduction in Cisplatin and 4OH-Tamoxifen Sensitivity in MCF-7 Breast Cancer Cells: The Influence of TNF-α
by: Nafiseh Sadat Alamolhodaei, et al.
Published: (2020-06-01)

Curcumin Induces Cell Death and Restores Tamoxifen Sensitivity in the Antiestrogen-Resistant Breast Cancer Cell Lines MCF-7/LCC2 and MCF-7/LCC9
by: Min Jiang, et al.
Published: (2013-01-01)

Meta-analysis of gene expression reveals ADM resistant to tamoxifen in human breast cancer MCF-7 cells
by: Wu, Pei-Chih, et al.
Published: (2017)

Recombinant human Erythropoietin enhanced the cytotoxic effects of tamoxifen toward the spheroid MCF-7 breast cancer cells
by: Hareth Y. Shujaa Edin, et al.
Published: (2021-09-01)

Molecular Mechanism of SAHA on Regulation of Autophagic Cell Death in Tamoxifen-Resistant MCF-7 Breast Cancer Cells
by: Young Ju Lee, A Jin Won, Jaewon Lee, Jee H. Jung, Sungpil Yoon, Byung Mu Lee, Hyung Sik Kim
Published: (2012-01-01)

Overexpression of Prolidase Induces Autophagic Death in MCF-7 Breast Cancer Cells
by: Ilona Zareba, et al.
Published: (2020-09-01)

The Synergistic Effects of Celastrol in combination with Tamoxifen on Apoptosis and Autophagy in MCF-7 Cells
by: Lijun Wang, et al.
Published: (2021-01-01)

Construction of recombinant sox2-encoding plasmids that regulate pluripotency of breast cancer stem cells from indonesian patient
by: Hanifah Rahmi, et al.
Published: (2019-05-01)

MTDH Mediates Estrogen-Independent Growth and Tamoxifen Resistance by Down-Regulating PTEN in MCF-7 Breast Cancer Cells
by: Chunyuan Xu, et al.
Published: (2014-05-01)

Tamoxifen Rechallenge Decreases Metastatic Potential but Increases Cell Viability and Clonogenicity in a Tamoxifen-Mediated Cytotoxicity-Resistant Subline of Human Breast MCF7 Cancer Cells
by: Yung-Chieh Chang, et al.
Published: (2020-06-01)

Correction to: Heregulin β1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells
by: Iain R. Hutcheson, et al.
Published: (2018-08-01)

Relative Expression of HIF-1α mRNA in Rat Heart, Brain and Blood During Induced Systemic Hypoxia
by: Syarifah Dewi, et al.
Published: (2009-11-01)

Aqueous Vernomia amygdalina Extracts Alter MCF-7 Cell Membrane Permeability and Efflux
by: Ernest B. Izevbigie, et al.
Published: (2006-06-01)

Tamoxifen and the PI3K Inhibitor: LY294002 Synergistically Induce Apoptosis and Cell Cycle Arrest in Breast Cancer MCF-7 Cells
by: Mohamed E. Abdallah, et al.
Published: (2020-07-01)

Combination of cyclopamine and tamoxifen promotes survival and migration of mcf-7 breast cancer cells--interaction of hedgehog-gli and estrogen receptor signaling pathways.
by: Maja Sabol, et al.
Published: (2014-01-01)

The active tamoxifen metabolite endoxifen (4OHNDtam) strongly down-regulates cytokeratin 6 (CK6) in MCF-7 breast cancer cells.
by: Thomas Helland, et al.
Published: (2015-01-01)

Overexpression of TMEM47 Induces Tamoxifen Resistance in Human Breast Cancer Cells
by: Xin Men, et al.
Published: (2021-03-01)

TNFR, TRAF2, NF-κB mRNA Levels of Glioblastoma Multiforme Cells Treated by Conditioned Medium of Umbilical Cord-derived Mesenchymal Stem Cells
by: Novi Silvia Hardiany, et al.
Published: (2019-08-01)

Tamoxifen for Breast Cancer
by: A Karn, et al.
Published: (2010-03-01)

The Effect of Tryptanthrin in MCF-7 Breast Cancer Cells
by: Yeh-Ssu Lin, et al.
Published: (2009)