Tumid lupus erythematosus: An intriguing dermatopathological connotation treated successfully with topical tacrolimus and hydroxyxhloroquine combination

• Main Authors: Prashant Verma, Sonal Sharma, Pravesh Yadav, Chaitanya Namdeo, Garima Mahajan
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2014-01-01
• Series: Indian Journal of Dermatology
• Subjects: Lupus erythematosus tumidus; tacrolimus; tumid lupus erythematosus
• Online Access: http://www.e-ijd.org/article.asp?issn=0019-5154;year=2014;volume=59;issue=2;spage=210;epage=210;aulast=Verma

Tumid lupus erythematosus (LE) is a rare variant of lupus erythematosus, which often follows a favorable course. A case of a young woman is illustrated, who presented with an asymptomatic erythematous, solitary plaque over her face. Histopathological and direct immunofluorescence examination established a diagnosis of tumid lupus erythematosus. She responded slowly and near-completely to hydroxychloroquine sulfate; however, a flare up occurred a month later. Addition of topical tacrolimus 0.1% resulted in complete regression without leaving any residual changes. No recurrence was seen subsequently.