Timescale of hole closure during plasma membrane repair estimated by calcium imaging and numerical modeling

Abstract Plasma membrane repair is essential for eukaryotic cell life and is triggered by the influx of calcium through membrane wounds. Repair consists of sequential steps, with closure of the membrane hole being the key event that allows the cell to recover, thus identifying the kinetics of hole c...

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Bibliographic Details
Main Authors: Martin Berg Klenow, Anne Sofie Busk Heitmann, Jesper Nylandsted, Adam Cohen Simonsen
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82926-6