Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that exert important functions in mediating the pleiotropic effects of diverse exogenous factors such as physical exercise and food components. Particularly, PPARs act as transcription factors that control the expression of ge...

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Main Authors:	Michele d’Angelo, Vanessa Castelli, Maria Grazia Tupone, Mariano Catanesi, Andrea Antonosante, Reyes Dominguez-Benot, Rodolfo Ippoliti, Anna Maria Cimini, Elisabetta Benedetti
Format:	Article
Language:	English
Published:	MDPI AG 2019-10-01
Series:	International Journal of Molecular Sciences
Subjects:	ppars inflammation lifestyle chronic diseases
Online Access:	https://www.mdpi.com/1422-0067/20/21/5422

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record_format	Article
spelling	doaj-cb4625164e4f48bbb20216e2931a3de32020-11-25T01:12:25ZengMDPI AGInternational Journal of Molecular Sciences1422-00672019-10-012021542210.3390/ijms20215422ijms20215422Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARsMichele d’Angelo0Vanessa Castelli1Maria Grazia Tupone2Mariano Catanesi3Andrea Antonosante4Reyes Dominguez-Benot5Rodolfo Ippoliti6Anna Maria Cimini7Elisabetta Benedetti8Department of Life, Health and Environmental Sciences, University of L’Aquila, 67100 L’Aquila, ItalyDepartment of Life, Health and Environmental Sciences, University of L’Aquila, 67100 L’Aquila, ItalyDepartment of Life, Health and Environmental Sciences, University of L’Aquila, 67100 L’Aquila, ItalyDepartment of Life, Health and Environmental Sciences, University of L’Aquila, 67100 L’Aquila, ItalyDepartment of Life, Health and Environmental Sciences, University of L’Aquila, 67100 L’Aquila, ItalyDepartment of Life, Health and Environmental Sciences, University of L’Aquila, 67100 L’Aquila, ItalyDepartment of Life, Health and Environmental Sciences, University of L’Aquila, 67100 L’Aquila, ItalyDepartment of Life, Health and Environmental Sciences, University of L’Aquila, 67100 L’Aquila, ItalyDepartment of Life, Health and Environmental Sciences, University of L’Aquila, 67100 L’Aquila, ItalyPeroxisome proliferator-activated receptors (PPARs) are nuclear receptors that exert important functions in mediating the pleiotropic effects of diverse exogenous factors such as physical exercise and food components. Particularly, PPARs act as transcription factors that control the expression of genes implicated in lipid and glucose metabolism, and cellular proliferation and differentiation. In this review, we aim to summarize the recent advancements reported on the effects of lifestyle and food habits on PPAR transcriptional activity in chronic disease.https://www.mdpi.com/1422-0067/20/21/5422pparsinflammationlifestylechronic diseases
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Michele d’Angelo Vanessa Castelli Maria Grazia Tupone Mariano Catanesi Andrea Antonosante Reyes Dominguez-Benot Rodolfo Ippoliti Anna Maria Cimini Elisabetta Benedetti
spellingShingle	Michele d’Angelo Vanessa Castelli Maria Grazia Tupone Mariano Catanesi Andrea Antonosante Reyes Dominguez-Benot Rodolfo Ippoliti Anna Maria Cimini Elisabetta Benedetti Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs International Journal of Molecular Sciences ppars inflammation lifestyle chronic diseases
author_facet	Michele d’Angelo Vanessa Castelli Maria Grazia Tupone Mariano Catanesi Andrea Antonosante Reyes Dominguez-Benot Rodolfo Ippoliti Anna Maria Cimini Elisabetta Benedetti
author_sort	Michele d’Angelo
title	Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs
title_short	Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs
title_full	Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs
title_fullStr	Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs
title_full_unstemmed	Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs
title_sort	lifestyle and food habits impact on chronic diseases: roles of ppars
publisher	MDPI AG
series	International Journal of Molecular Sciences
issn	1422-0067
publishDate	2019-10-01
description	Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that exert important functions in mediating the pleiotropic effects of diverse exogenous factors such as physical exercise and food components. Particularly, PPARs act as transcription factors that control the expression of genes implicated in lipid and glucose metabolism, and cellular proliferation and differentiation. In this review, we aim to summarize the recent advancements reported on the effects of lifestyle and food habits on PPAR transcriptional activity in chronic disease.
topic	ppars inflammation lifestyle chronic diseases
url	https://www.mdpi.com/1422-0067/20/21/5422
work_keys_str_mv	AT micheledangelo lifestyleandfoodhabitsimpactonchronicdiseasesrolesofppars AT vanessacastelli lifestyleandfoodhabitsimpactonchronicdiseasesrolesofppars AT mariagraziatupone lifestyleandfoodhabitsimpactonchronicdiseasesrolesofppars AT marianocatanesi lifestyleandfoodhabitsimpactonchronicdiseasesrolesofppars AT andreaantonosante lifestyleandfoodhabitsimpactonchronicdiseasesrolesofppars AT reyesdominguezbenot lifestyleandfoodhabitsimpactonchronicdiseasesrolesofppars AT rodolfoippoliti lifestyleandfoodhabitsimpactonchronicdiseasesrolesofppars AT annamariacimini lifestyleandfoodhabitsimpactonchronicdiseasesrolesofppars AT elisabettabenedetti lifestyleandfoodhabitsimpactonchronicdiseasesrolesofppars
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Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs

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