A single amino acid substitution in the core protein of West Nile virus increases resistance to acidotropic compounds.

West Nile virus (WNV) is a worldwide distributed mosquito-borne flavivirus that naturally cycles between birds and mosquitoes, although it can infect multiple vertebrate hosts including horses and humans. This virus is responsible for recurrent epidemics of febrile illness and encephalitis, and has...

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Bibliographic Details
Main Authors: Miguel A Martín-Acebes, Ana-Belén Blázquez, Nereida Jiménez de Oya, Estela Escribano-Romero, Pei-Yong Shi, Juan-Carlos Saiz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3715472?pdf=render