Postirradiation Multiple Minute Digitate Porokeratosis: Case Report

Docetaxel is a second-generation taxane commonly used in the treatment of advanced malignant tumours such as breast adenocarcinoma. We describe the case of a 67-year-old female undergoing adjuvant chemotherapy with docetaxel for invasive ductal carcinoma of the left breast presenting with typical p...

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Bibliographic Details
Main Authors: Joana Lima, Marta Sousa, Pedro Andrade
Format: Article
Language:English
Published: Sociedade Portuguesa de Dermatologia e Venereologia 2018-01-01
Series:Revista da Sociedade Portuguesa de Dermatologia e Venereologia
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Online Access:https://revista.spdv.com.pt/index.php/spdv/article/view/798
Description
Summary:Docetaxel is a second-generation taxane commonly used in the treatment of advanced malignant tumours such as breast adenocarcinoma. We describe the case of a 67-year-old female undergoing adjuvant chemotherapy with docetaxel for invasive ductal carcinoma of the left breast presenting with typical psoriatic lesions on the dorsum and limbs - the most representative of them arising close to the venous access for docetaxel infusion. No personal or family history of psoriasis was reported. The patient started and maintained treatment with oral acitretin and topical betamethasone diproprionate/calcipotriol for nearly eight months, with almost complete regression of cutaneous lesions. Drug-induced psoriasis is a rare condition. The most commonly reported drugs include beta-blockers, interferon and antimalarials. In this case we demonstrate that docetaxel should be included in the group of drugs that can potentially induce psoriasis.
ISSN:2182-2395
2182-2409