Rhabdomyolysis due to the additive effect of statin therapy and hypothyroidism: a case report

<p>Abstract</p> <p>We describe a patient with previously undiagnosed hypothyroidism who developed rhabdomyolysis while taking a statin. He had no other precipitating factors. The statin was stopped, intravenous fluids were started immediately and L-thyroxin was given after confirmi...

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Bibliographic Details
Main Authors: Yeter Ekrem, Keles Telat, Durmaz Tahir, Bozkurt Engin
Format: Article
Language:English
Published: BMC 2007-11-01
Series:Journal of Medical Case Reports
Online Access:http://www.jmedicalcasereports.com/content/1/1/130
Description
Summary:<p>Abstract</p> <p>We describe a patient with previously undiagnosed hypothyroidism who developed rhabdomyolysis while taking a statin. He had no other precipitating factors. The statin was stopped, intravenous fluids were started immediately and L-thyroxin was given after confirming the diagnosis of hypothyroidism. His symptoms improved over a few days. Because rhabdomyolysis is a rare but potentially life threatening disorder when complicated by acute tubular necrosis and renal failure, physicians must pay special attention when starting statins in patients with hyperlipidemia.</p>
ISSN:1752-1947