Effect of different hip replacement methods under minimally invasive anterolateral approach on bone metabolism and joint pain in patients with femoral neck fracture
Objective: To explore the effect of different hip replacement methods under minimally invasive anterolateral approach on bone metabolism and joint pain in patients with femoral neck fracture. Methods: A total of 110 patients with femoral neck fracture who were treated in Ruijin Hospital North, Sh...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Editorial Board of Journal of Hainan Medical University
2017-10-01
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| Series: | Journal of Hainan Medical University |
| Subjects: | |
| Online Access: | http://www.hnykdxxb.com/PDF/201720/13.pdf |
| Summary: | Objective: To explore the effect of different hip replacement methods under minimally
invasive anterolateral approach on bone metabolism and joint pain in patients with femoral
neck fracture. Methods: A total of 110 patients with femoral neck fracture who were treated
in Ruijin Hospital North, Shanghai Jiaotong University School of Medicine between July
2015 and January 2017 were collected and divided into control group and observation group
by random number table, each with 55 cases. Control group accepted half hip replacement
under minimally invasive anterolateral approach, and observation group accepted total hip
replacement under minimally invasive anterolateral approach. The differences in contents of
bone metabolism and joint pain-related indexes were compared between the two groups before
and after surgery. Results: Before surgery, serum contents of bone formation indexes, bone
resorption indexes, inflammatory indexes and pain mediators were not statistically significant
between the two groups. 1 month after surgery, serum bone formation indexes PINP, BAP
and BGP contents of observation group were higher than those of control group; serum bone
resorption indexes β-CTX and TRACP-5b contents were lower than those of control group;
serum inflammatory indexes IL-1 and TNF-α contents were lower than those of control
group; serum pain mediators 5-HT and PGE2 contents were lower than those of control group.
Conclusion: Total hip replacement under minimally invasive anterolateral approach is more
effective to promote the formation of bone formation/bone resorption balance and reduce the
joint pain. |
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| ISSN: | 1007-1237 1007-1237 |