Age-Related Differences in Muscle Synergy Organization during Step Ascent at Different Heights and Directions

• Main Authors: Remco J. Baggen, Jaap H. van Dieën, Evelien Van Roie, Sabine M. Verschueren, Georgios Giarmatzis, Christophe Delecluse, Nadia Dominici
• Format: Article
• Language: English
• Published: MDPI AG 2020-03-01
• Series: Applied Sciences
• Subjects: emg; muscle synergies; forward stepping; lateral stepping; aging; neural control
• Online Access: https://www.mdpi.com/2076-3417/10/6/1987

The aim of this study was to explore the underlying age-related differences in dynamic motor control during different step ascent conditions using muscle synergy analysis. Eleven older women (67.0 <i>y</i> &#177; 2.5) and ten young women (22.5 <i>y</i> &#177; 1.6) performed stepping in forward and lateral directions at step heights of 10, 20 and 30 cm. Surface electromyography was obtained from 10 lower limb and torso muscles. Non-negative matrix factorization was used to identify sets of (<i>n</i>) synergies across age groups and stepping conditions. In addition, variance accounted for (VAF) by the detected number of synergies was compared to assess complexity of motor control. Finally, correlation coefficients of muscle weightings and between-subject variability of the temporal activation patterns were calculated and compared between age groups and stepping conditions. Four synergies accounted for &gt;85% VAF across age groups and stepping conditions. Age and step height showed a significant negative correlation with VAF during forward stepping but not lateral stepping, with lower VAF indicating higher synergy complexity. Muscle weightings showed higher similarity across step heights in older compared to young women. Neuromuscular control of young and community-dwelling older women could not be differentiated based on the number of synergies extracted. Additional analyses of synergy structure and complexity revealed subtle age- and step-height-related differences, indicating that older women rely on more complex neuromuscular control strategies.