Effect of codeine on CYP450 isoform activity of rats

Effect of codeine on CYP450 isoform activity of rats

Context: Codeine, also known as 3-methylmorphine, is an opiate used to treat pain, as a cough medicine and for diarrhoea. No study on the effects of codeine on the metabolic capacity of CYP enzyme is reported. Objective: In order to investigate the effects of codeine on the metabolic capacity of cyt...

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Bibliographic Details
Main Authors: Shuanghu Wang, Yanwen Dong, Ke Su, Jing Zhang, Linyi Wang, Anyue Han, Congcong Wen, Xianqin Wang, Yan He
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Pharmaceutical Biology
Subjects:
cocktail
uplc-ms/ms
bupropion
midazolam
biochemical
Online Access:http://dx.doi.org/10.1080/13880209.2017.1297466

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