Replication Validity of Initial Association Studies: A Comparison between Psychiatry, Neurology and Four Somatic Diseases.
CONTEXT:There are growing concerns about effect size inflation and replication validity of association studies, but few observational investigations have explored the extent of these problems. OBJECTIVE:Using meta-analyses to measure the reliability of initial studies and explore whether this varies...
Main Authors: | Estelle Dumas-Mallet, Katherine Button, Thomas Boraud, Marcus Munafo, François Gonon |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4919034?pdf=render |
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