Scaffolds with a High Surface Area-to-Volume Ratio and Cultured Under Fast Flow Perfusion Result in Optimal O<sub>2</sub> Delivery to the Cells in Artificial Bone Tissues

Scaffolds with a High Surface Area-to-Volume Ratio and Cultured Under Fast Flow Perfusion Result in Optimal O<sub>2</sub> Delivery to the Cells in Artificial Bone Tissues

Tissue engineering has the potential for repairing large bone defects, which impose a heavy financial burden on the public health. However, difficulties with O<sub>2</sub> delivery to the cells residing in the interior of tissue engineering scaffolds make it challenging to grow artificia...

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Bibliographic Details
Main Authors: Thanh Danh Nguyen, Olufemi E. Kadri, Vassilios I. Sikavitsas, Roman S. Voronov
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Applied Sciences
Subjects:
oxygen delivery
optimization
mass transfer
transport
bone tissue engineering
computational fluid dynamics
Lattice Boltzmann method
scaffold design
culturing protocol
Lagrangian scalar tracking
Online Access:https://www.mdpi.com/2076-3417/9/11/2381

Internet

https://www.mdpi.com/2076-3417/9/11/2381

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