Human liver stem cells attenuate concanavalin A-induced acute liver injury by modulating myeloid-derived suppressor cells and CD4+ T cells in mice

Human liver stem cells attenuate concanavalin A-induced acute liver injury by modulating myeloid-derived suppressor cells and CD4+ T cells in mice

Abstract Background Acute liver failure (ALF) is a serious threat to the life of people all over the world. Finding an effective way to manage ALF is important. Human liver stem cells (HLSCs) are early undifferentiated cells that have been implicated in the regeneration and functional reconstruction...

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Bibliographic Details
Main Authors: Yanzhen Bi, Jiannan Li, Yonghong Yang, Quanyi Wang, Quanquan Wang, Xiaobei Zhang, Guanjun Dong, Yibo Wang, Zhongping Duan, Zhenfeng Shu, Tongjun Liu, Yu Chen, Kai Zhang, Feng Hong
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Stem Cell Research & Therapy
Subjects:
Acute liver injury
Human liver stem cells
MDSCs
CD4+ T cells
Concanavalin A
Online Access:http://link.springer.com/article/10.1186/s13287-018-1128-2

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