Pancreatic β-cell regeneration: advances in understanding the genes and signaling pathways involved

Editorial summary Recent advances in β-cell regeneration in vivo are providing insights into the mechanisms involved in the conversion of distinct pancreatic cell lineages into β cells. These mechanisms mostly involve reactivation of the gene encoding the pancreatic endocrine cell-specifying transcr...

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Main Authors: Solomon Afelik, Meritxell Rovira
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Genome Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13073-017-0437-x
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spelling doaj-caf83d462bee49b1863656db157d452e2020-11-24T22:00:11ZengBMCGenome Medicine1756-994X2017-05-01911410.1186/s13073-017-0437-xPancreatic β-cell regeneration: advances in understanding the genes and signaling pathways involvedSolomon Afelik0Meritxell Rovira1Division of Transplantation, Department of Surgery, University of Illinois at ChicagoCenter of Regenerative Medicine in Barcelona (CMRB)Editorial summary Recent advances in β-cell regeneration in vivo are providing insights into the mechanisms involved in the conversion of distinct pancreatic cell lineages into β cells. These mechanisms mostly involve reactivation of the gene encoding the pancreatic endocrine cell-specifying transcription factor neurogenin-3.http://link.springer.com/article/10.1186/s13073-017-0437-xAcinar CellDuctal CellPancreatic Acinar CellArtemetherCell Conversion
collection DOAJ
language English
format Article
sources DOAJ
author Solomon Afelik
Meritxell Rovira
spellingShingle Solomon Afelik
Meritxell Rovira
Pancreatic β-cell regeneration: advances in understanding the genes and signaling pathways involved
Genome Medicine
Acinar Cell
Ductal Cell
Pancreatic Acinar Cell
Artemether
Cell Conversion
author_facet Solomon Afelik
Meritxell Rovira
author_sort Solomon Afelik
title Pancreatic β-cell regeneration: advances in understanding the genes and signaling pathways involved
title_short Pancreatic β-cell regeneration: advances in understanding the genes and signaling pathways involved
title_full Pancreatic β-cell regeneration: advances in understanding the genes and signaling pathways involved
title_fullStr Pancreatic β-cell regeneration: advances in understanding the genes and signaling pathways involved
title_full_unstemmed Pancreatic β-cell regeneration: advances in understanding the genes and signaling pathways involved
title_sort pancreatic β-cell regeneration: advances in understanding the genes and signaling pathways involved
publisher BMC
series Genome Medicine
issn 1756-994X
publishDate 2017-05-01
description Editorial summary Recent advances in β-cell regeneration in vivo are providing insights into the mechanisms involved in the conversion of distinct pancreatic cell lineages into β cells. These mechanisms mostly involve reactivation of the gene encoding the pancreatic endocrine cell-specifying transcription factor neurogenin-3.
topic Acinar Cell
Ductal Cell
Pancreatic Acinar Cell
Artemether
Cell Conversion
url http://link.springer.com/article/10.1186/s13073-017-0437-x
work_keys_str_mv AT solomonafelik pancreaticbcellregenerationadvancesinunderstandingthegenesandsignalingpathwaysinvolved
AT meritxellrovira pancreaticbcellregenerationadvancesinunderstandingthegenesandsignalingpathwaysinvolved
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