Piezo1 links mechanical forces to red blood cell volume

Piezo1 links mechanical forces to red blood cell volume

Red blood cells (RBCs) experience significant mechanical forces while recirculating, but the consequences of these forces are not fully understood. Recent work has shown that gain-of-function mutations in mechanically activated Piezo1 cation channels are associated with the dehydrating RBC disease x...

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Bibliographic Details
Main Authors: Stuart M Cahalan, Viktor Lukacs, Sanjeev S Ranade, Shu Chien, Michael Bandell, Ardem Patapoutian
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-05-01
Series:eLife
Subjects:
red blood cell
mechanotransduction
physiology
cell volume regulation
knockout animal
Online Access:https://elifesciences.org/articles/07370

Internet

https://elifesciences.org/articles/07370

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