An engineered CRISPR-Cas12a variant and DNA-RNA hybrid guides enable robust and rapid COVID-19 testing
As the COVID-19 pandemic continues, variants of the virus are emerging. Here the authors present a diagnostic assay that can detect wildtype and known variants using engineered Cas12a.
Bibliographic Details
| Main Authors: |
Kean Hean Ooi,
Mengying Mandy Liu,
Jie Wen Douglas Tay,
Seok Yee Teo,
Pornchai Kaewsapsak,
Shengyang Jin,
Chun Kiat Lee,
Jingwen Hou,
Sebastian Maurer-Stroh,
Weisi Lin,
Benedict Yan,
Gabriel Yan,
Yong-Gui Gao,
Meng How Tan |
|---|
| Format: | Article
|
|---|
| Language: | English |
|---|
| Published: |
Nature Publishing Group
2021-03-01
|
|---|
| Series: | Nature Communications
|
|---|
| Online Access: | https://doi.org/10.1038/s41467-021-21996-6
|
|---|
