A study of risk factors and predictive factors in intraoperative floppy iris syndrome during phacoemulsification

• Main Authors: Jie-Xin Yu, Ke Yao
• Format: Article
• Language: English
• Published: Press of International Journal of Ophthalmology (IJO PRESS) 2017-11-01
• Series: Guoji Yanke Zazhi
• Subjects: intraoperative floppy iris syndrome; risk factors; predictive factors; complication
• Online Access: http://ies.ijo.cn/cn_publish/2017/11/201711033.pdf

AIM: To determine the incidence of intraoperative floppy iris syndrome(IFIS)in patients undergoing phacoemulsification in a Chinese hospital, and to assess new risk factors and predictive factors for IFIS. <p>METHODS: A prospective, observational case series. In the consecutive cataract surgeries performed in one year, the medicine administration, pupil size(PS)before and after mydriasis, and signs of IFIS were recorded. <p>RESULTS: Totally 807 patients(1 068 eyes)underwent cataract surgeries. Among the 1 068 eyes, signs of IFIS were noted in 34 eyes. Strong positive correlations were showed between finasteride(6.4%, <i>OR</i>=5.885), tamsulosin(25%, <i>OR</i>=21.578), reserpine(16.7%, <i>OR</i>=12.947), clozapine(66.7%, <i>OR</i>=139.467), post-panretinal photocoagulation(14.3%, <i>OR</i>=10.789)and IFIS. Pupil size was inversely related to IFIS incidence(<i>P</i><0.001). A dilated pupil smaller than 7.25mm could predict IFIS(<i>P</i><0.001). <p>CONCLUSION: The incidence rate of IFIS was 3.18%. Reserpine, clozapine and post-panretinal photocoagulation emerged as new risk factors for IFIS. A small dilated pupil may imply IFIS occurrence.