Metabolic vulnerabilities of metastasizing cancer cells

Abstract Most cancer patients die due to metastasis formation. Therefore, understanding, preventing, and treating metastatic cancers is an unmet need. Recent research indicates that cancer cells that undergo metastasis formation have a distinct metabolism that can be targeted. Here, I would like to...

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Main Author: Sarah-Maria Fendt
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Biology
Online Access:http://link.springer.com/article/10.1186/s12915-019-0672-2
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spelling doaj-cadaffc94d6d4ede8fb647da99e626fc2020-11-25T03:36:42ZengBMCBMC Biology1741-70072019-07-011711410.1186/s12915-019-0672-2Metabolic vulnerabilities of metastasizing cancer cellsSarah-Maria Fendt0Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer BiologyAbstract Most cancer patients die due to metastasis formation. Therefore, understanding, preventing, and treating metastatic cancers is an unmet need. Recent research indicates that cancer cells that undergo metastasis formation have a distinct metabolism that can be targeted. Here, I would like to discuss potential opportunities in exploiting the metabolic vulnerabilities of metastasizing cancer cells.http://link.springer.com/article/10.1186/s12915-019-0672-2
collection DOAJ
language English
format Article
sources DOAJ
author Sarah-Maria Fendt
spellingShingle Sarah-Maria Fendt
Metabolic vulnerabilities of metastasizing cancer cells
BMC Biology
author_facet Sarah-Maria Fendt
author_sort Sarah-Maria Fendt
title Metabolic vulnerabilities of metastasizing cancer cells
title_short Metabolic vulnerabilities of metastasizing cancer cells
title_full Metabolic vulnerabilities of metastasizing cancer cells
title_fullStr Metabolic vulnerabilities of metastasizing cancer cells
title_full_unstemmed Metabolic vulnerabilities of metastasizing cancer cells
title_sort metabolic vulnerabilities of metastasizing cancer cells
publisher BMC
series BMC Biology
issn 1741-7007
publishDate 2019-07-01
description Abstract Most cancer patients die due to metastasis formation. Therefore, understanding, preventing, and treating metastatic cancers is an unmet need. Recent research indicates that cancer cells that undergo metastasis formation have a distinct metabolism that can be targeted. Here, I would like to discuss potential opportunities in exploiting the metabolic vulnerabilities of metastasizing cancer cells.
url http://link.springer.com/article/10.1186/s12915-019-0672-2
work_keys_str_mv AT sarahmariafendt metabolicvulnerabilitiesofmetastasizingcancercells
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