Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans

Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans

Lung cancer etiology has largely been studied in homogenous populations of European descent. Here, targeted sequencing in African American lung adenocarcinomas finds significantly higher prevalence of PTPRTand JAK2 mutations, validated independently by whole exome sequencing, highlighting potentiall...

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Bibliographic Details
Main Authors: Khadijah A. Mitchell, Noah Nichols, Wei Tang, Jennifer Walling, Holly Stevenson, Marbin Pineda, Roxana Stefanescu, Daniel C. Edelman, Andrew T. Girvin, Adriana Zingone, Sanju Sinha, Elise Bowman, Emily L. Rossi, Rony F. Arauz, Yuelin Jack Zhu, Justin Lack, Elizabeth Weingartner, Joshua J. Waterfall, Sharon R. Pine, John Simmons, Paul Meltzer, Bríd M. Ryan
Format: Article
Language:English
Published: Nature Publishing Group 2019-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13732-y

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