Neuropathy-related mutations alter the membrane binding properties of the human myelin protein P0 cytoplasmic tail.

Neuropathy-related mutations alter the membrane binding properties of the human myelin protein P0 cytoplasmic tail.

Schwann cells myelinate selected axons in the peripheral nervous system (PNS) and contribute to fast saltatory conduction via the formation of compact myelin, in which water is excluded from between tightly adhered lipid bilayers. Peripheral neuropathies, such as Charcot-Marie-Tooth disease (CMT) an...

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Bibliographic Details
Main Authors: Arne Raasakka, Salla Ruskamo, Robert Barker, Oda C Krokengen, Guro H Vatne, Cecilie K Kristiansen, Erik I Hallin, Maximilian W A Skoda, Ulrich Bergmann, Hanna Wacklin-Knecht, Nykola C Jones, Søren V Hoffmann, Petri Kursula
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0216833

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https://doi.org/10.1371/journal.pone.0216833

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