Apoptosis resistance in chronic myelogenous leukemia

Apoptosis resistance in chronic myelogenous leukemia

The chronic myeloid leukemia (CML) is the three-phasemyeloproliferative disorder, dependent on the expression of theoncoprotein Bcr-Abl, which is the product of the reciprocaltranslocation between chromosomes 9 and 22, resulting in thePhiladelphia chromosome (Ph). Bcr-Abl protein is the constitutive...

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Bibliographic Details
Main Authors:	Fabíola Attié de Castro, Jacqueline de Fátima Jacysyn, Ana Elisa Bueno-da-Silva, Nelson Hamerschlak, Gustavo Pessini Amarante-Mendes
Format:	Article
Language:	English
Published:	Instituto Israelita de Ensino e Pesquisa Albert Einstein 2005-09-01
Series:	Einstein (São Paulo)
Subjects:	Chronic myeloid leukemia/therapy Apoptosis Fusion proteins bcr-abl Oncogene proteins
Online Access:	http://www.einstein.br/revista/biblioteca/artigos/vol3/num_3/Vol3_N3_P207.pdf

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