Rift Valley Fever Vaccine Virus Clone 13 Is Able to Cross the Ovine Placental Barrier Associated with Foetal Infections, Malformations, and Stillbirths.

Rift Valley Fever Vaccine Virus Clone 13 Is Able to Cross the Ovine Placental Barrier Associated with Foetal Infections, Malformations, and Stillbirths.

Rift Valley fever virus (RVFV) is a mosquito-borne pathogen that affects domesticated ruminants and occasionally humans. Classical RVF vaccines are based on formalin-inactivated virus or the live-attenuated Smithburn strain. The inactivated vaccine is highly safe but requires multiple administration...

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Bibliographic Details
Main Authors: Birgit Makoschey, Emma van Kilsdonk, Willem R Hubers, Mieke P Vrijenhoek, Marianne Smit, Paul J Wichgers Schreur, Jeroen Kortekaas, Véronique Moulin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4816553?pdf=render

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