Role of endogenous GLP-1 and GIP in beta cell compensatory responses to insulin resistance and cellular stress.

Role of endogenous GLP-1 and GIP in beta cell compensatory responses to insulin resistance and cellular stress.

Role of GLP-1 and GIP in beta cell compensatory responses to beta cell attack and insulin resistance were examined in C57BL/6 mice lacking functional receptors for GLP-1 and GIP. Mice were treated with multiple low dose streptozotocin or hydrocortisone. Islet parameters were assessed by immunohistoc...

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Bibliographic Details
Main Authors:	Srividya Vasu, R Charlotte Moffett, Bernard Thorens, Peter R Flatt
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4072716?pdf=render

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