Brain-derived neurotrophic factor protects against acrylamide-induced neuronal and synaptic injury via the TrkB-MAPK-Erk1/2 pathway

Brain-derived neurotrophic factor protects against acrylamide-induced neuronal and synaptic injury via the TrkB-MAPK-Erk1/2 pathway

Acrylamide has been shown to be neurotoxic. Brain-derived neurotrophic factor (BDNF) can alleviate acrylamide-induced synaptic injury; however, the underlying mechanism remains unclear. In this study, dibutyryl-cyclic adenosine monophosphate-induced mature human neuroblastoma (NB-1) cells were expos...

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Bibliographic Details
Main Authors: Xiao Chen, Jing-Wei Xiao, Peng Cao, Yi Zhang, Wen-Jian Cai, Jia-Yang Song, Wei-Min Gao, Bin Li
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
factor; injury; pathway; peripheral nerve; protection; protein; regeneration; repair
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=1;spage=150;epage=157;aulast=Chen

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