The p53 Pathway in Glioblastoma

The p53 Pathway in Glioblastoma

The tumor suppressor and transcription factor p53 plays critical roles in tumor prevention by orchestrating a wide variety of cellular responses, including damaged cell apoptosis, maintenance of genomic stability, inhibition of angiogenesis, and regulation of cell metabolism and tumor microenvironme...

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Bibliographic Details
Main Authors: Ying Zhang, Collin Dube, Myron Gibert, Nichola Cruickshanks, Baomin Wang, Maeve Coughlan, Yanzhi Yang, Initha Setiady, Ciana Deveau, Karim Saoud, Cassandra Grello, Madison Oxford, Fang Yuan, Roger Abounader
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Cancers
Subjects:
glioblastoma
wild type p53
mutant p53
gain-of-function
Online Access:http://www.mdpi.com/2072-6694/10/9/297

Internet

http://www.mdpi.com/2072-6694/10/9/297

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