Construction of <it>Bordetella pertussis </it>strains with enhanced production of genetically-inactivated Pertussis Toxin and Pertactin by unmarked allelic exchange

Construction of <it>Bordetella pertussis </it>strains with enhanced production of genetically-inactivated Pertussis Toxin and Pertactin by unmarked allelic exchange

<p>Abstract</p> <p>Background</p> <p>Acellular Pertussis vaccines against whooping cough caused by <it>Bordetella pertussis </it>present a much-improved safety profile compared to the original vaccine of killed whole cells. The principal antigen of acellular...

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Bibliographic Details
Main Authors: Buasri Wasin, Impoolsup Attawut, Boonchird Chuenchit, Luengchaichawange Anocha, Prompiboon Pannipa, Petre Jean, Panbangred Watanalai
Format: Article
Language:English
Published: BMC 2012-04-01
Series:BMC Microbiology
Online Access:http://www.biomedcentral.com/1471-2180/12/61

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