Exosomal-mediated transfer of OIP5-AS1 enhanced cell chemoresistance to trastuzumab in breast cancer via up-regulating HMGB3 by sponging miR-381-3p

Exosomal-mediated transfer of OIP5-AS1 enhanced cell chemoresistance to trastuzumab in breast cancer via up-regulating HMGB3 by sponging miR-381-3p

Long noncoding RNA OPA-interacting protein 5 antisense transcript 1 (OIP5-AS1) was confirmed to involve in the malignancy of breast cancer. However, whether exosomal OIP5-AS1 is implicated in trastuzumab resistance remains unclear.

Bibliographic Details
Main Authors: Yu Qiang, Li Yinmou, Peng Shijun, Li Jing, Qin Xianxiong
Format: Article
Language:English
Published: De Gruyter 2021-03-01
Series:Open Medicine
Subjects:
oip5-as1
mir-381-3p
hmgb3
breast cancer
exosomes
chemoresistance
Online Access:https://doi.org/10.1515/med-2021-0249
Description
Summary:Long noncoding RNA OPA-interacting protein 5 antisense transcript 1 (OIP5-AS1) was confirmed to involve in the malignancy of breast cancer. However, whether exosomal OIP5-AS1 is implicated in trastuzumab resistance remains unclear.
ISSN:2391-5463

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