Sanger sequencing of MMR genes in a one-plate system

Both incidence and mortality of colorectal cancer (CRC) in Romania have shown a continuous increase during the last decades. Hereditary Non-Polyposic Colorectal Cancer (HNPCC), also known as Lynch syndrome, is mainly attributable to mismatch repair (MMR) genes MSH2, MSH6, and MLH1. Individuals carry...

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Bibliographic Details
Main Authors: Negura Lucian, Negura Anca
Format: Article
Language:English
Published: Sciendo 2018-04-01
Series:Romanian Journal of Laboratory Medicine
Subjects:
Online Access:https://doi.org/10.2478/rrlm-2018-0008