Exome sequencing identifies novel somatic variants in African American esophageal squamous cell carcinoma

Abstract Esophageal cancer has a strikingly low survival rate mainly due to the lack of diagnostic markers for early detection and effective therapies. In the U.S., 75% of individuals diagnosed with esophageal squamous cell carcinoma (ESCC) are of African descent. African American ESCC (AA ESCC) is...

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Bibliographic Details
Main Authors: Hayriye Verda Erkizan, Shrey Sukhadia, Thanemozhi G. Natarajan, Gustavo Marino, Vicente Notario, Jack H. Lichy, Robert G. Wadleigh
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94064-0