Nanomaterials for Tumor Hypoxia Relief to Improve the Efficacy of ROS-Generated Cancer Therapy

Nanomaterials for Tumor Hypoxia Relief to Improve the Efficacy of ROS-Generated Cancer Therapy

Given the fact that excessive levels of reactive oxygen species (ROS) induce damage to proteins, lipids, and DNA, various ROS-generating agents and strategies have been explored to induce cell death and tumor destruction by generating ROS above toxic threshold. Unfortunately, hypoxia in tumor microe...

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Bibliographic Details
Main Authors: Changping Ruan, Kaihua Su, Dongmin Zhao, Ai Lu, Chaoran Zhong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Chemistry
Subjects:
reactive oxygen species
tumor hypoxia
cancer therapy
nanomaterials
O2 supply
tumor oxygenation
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.649158/full

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