Cisplatin-Induced Giant Cells Formation Is Involved in Chemoresistance of Melanoma Cells

Cisplatin-Induced Giant Cells Formation Is Involved in Chemoresistance of Melanoma Cells

Melanoma is notoriously resistant to current cancer therapy. However, the chemoresistance mechanism of melanoma remains unclear. The present study unveiled that chemotherapy drug cisplatin induced the formation of giant cells, which exhibited enlargement in cell diameter and nucleus in mice and huma...

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Bibliographic Details
Main Authors:	Chien-Hui Weng, Chieh-Shan Wu, Jian-Ching Wu, Mei-Lang Kung, Ming-Hsiu Wu, Ming-Hong Tai
Format:	Article
Language:	English
Published:	MDPI AG 2020-10-01
Series:	International Journal of Molecular Sciences
Subjects:	melanoma chemoresistance cisplatin giant cell stemness
Online Access:	https://www.mdpi.com/1422-0067/21/21/7892

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