Estimating HIV-1 fitness characteristics from cross-sectional genotype data.

Estimating HIV-1 fitness characteristics from cross-sectional genotype data.

Despite the success of highly active antiretroviral therapy (HAART) in the management of human immunodeficiency virus (HIV)-1 infection, virological failure due to drug resistance development remains a major challenge. Resistant mutants display reduced drug susceptibilities, but in the absence of dr...

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Bibliographic Details
Main Authors: Sathej Gopalakrishnan, Hesam Montazeri, Stephan Menz, Niko Beerenwinkel, Wilhelm Huisinga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4222584?pdf=render

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