Role of the Polycystins in Cell Migration, Polarity, and Tissue Morphogenesis
Cystic kidney diseases (CKD) is a class of disorders characterized by ciliary dysfunction and, therefore, belonging to the ciliopathies. The prototype CKD is autosomal dominant polycystic kidney disease (ADPKD), whose mutated genes encode for two membrane-bound proteins, polycystin-1 (PC-1) and poly...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2015-10-01
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| Series: | Cells |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2073-4409/4/4/687 |