THERMODYNAMIC PARAMETERS OF SOLUTIONS OF SILDENAFIL CITRATE IN SOME ORGANIC SOLVENTS AT DIFFERENT TEMPERATURES

The solubility of Sildenafil citrate in some organic solvents; hexane, toluene,1-butanol and 1,2 dichloroethane has been determined using gravimetric method over different temperature range (298.15 K to 328.15 K) at one atmospheric pressure. The modified Apelblat and Buchowski-Ksiazczak λh equations...

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Bibliographic Details
Main Authors: S. Baluja, K. Bhesaniya
Format: Article
Language:English
Published: El Oued University 2014-06-01
Series:Journal of Fundamental and Applied Sciences
Online Access:http://old.jfas.info/index.php/JFAS/article/view/252/pdf
Description
Summary:The solubility of Sildenafil citrate in some organic solvents; hexane, toluene,1-butanol and 1,2 dichloroethane has been determined using gravimetric method over different temperature range (298.15 K to 328.15 K) at one atmospheric pressure. The modified Apelblat and Buchowski-Ksiazczak λh equations were used to correlate the experimental solubility data. Further, various thermodynamic parameters have been evaluated from these solubility data.
ISSN:1112-9867