Metformin Regulates the Expression of CD133 Through the AMPK-CEBPβ Pathway in Hepatocellular Carcinoma Cell Lines
CD133 is a cellular surface protein, which has been reported to be a cancer stem cell marker, and thus is considered a potential target for cancer treatment. Metformin, one of the biguanides used for the treatment of diabetes, is also known to reduce the risk of cancer development and cancer stem-li...
Main Authors: | Osamu Maehara, Shunsuke Ohnishi, Ayaka Asano, Goki Suda, Mitsuteru Natsuizaka, Koji Nakagawa, Masanobu Kobayashi, Naoya Sakamoto, Hiroshi Takeda |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-06-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558619300624 |
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