Opistorchis felineus invasion influence on immunity in bronchial asthma
To investigate the molecular mechanisms of human immune response modification by Opisthorchis felineus antigens in bronchial asthma. The experimental study was performed with cell cultures from patients with bronchial asthma, patients with opisthorchiasis, and patients with BA and opisthorchiasis co...
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Siberian State Medical University (Tomsk)
2010-06-01
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Series: | Bûlleten' Sibirskoj Mediciny |
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Online Access: | https://bulletin.tomsk.ru/jour/article/view/1601 |
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doaj-ca20301075cf4d46b232858a978dbd582021-07-29T08:37:52ZengSiberian State Medical University (Tomsk)Bûlleten' Sibirskoj Mediciny1682-03631819-36842010-06-0193859010.20538/1682-0363-2010-3-85-901104Opistorchis felineus invasion influence on immunity in bronchial asthmaL. M. Ogorodova0M. B. Freidin1A. E. Sazonov2O. S. Fyodorova3I. A. Deyev4Ye. E. Kremer5Сибирский государственный медицинский университетНИИ медицинской генетики СО РАМНСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетTo investigate the molecular mechanisms of human immune response modification by Opisthorchis felineus antigens in bronchial asthma. The experimental study was performed with cell cultures from patients with bronchial asthma, patients with opisthorchiasis, and patients with BA and opisthorchiasis co-occurred. A proposed down-regulation of immune response by higher level of IL10 and TGFB genes expression in patients with opisthorchiasis was revealed.https://bulletin.tomsk.ru/jour/article/view/1601opisthorchis felineus invasionbronchial asthmaimmunitygene expression |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
L. M. Ogorodova M. B. Freidin A. E. Sazonov O. S. Fyodorova I. A. Deyev Ye. E. Kremer |
spellingShingle |
L. M. Ogorodova M. B. Freidin A. E. Sazonov O. S. Fyodorova I. A. Deyev Ye. E. Kremer Opistorchis felineus invasion influence on immunity in bronchial asthma Bûlleten' Sibirskoj Mediciny opisthorchis felineus invasion bronchial asthma immunity gene expression |
author_facet |
L. M. Ogorodova M. B. Freidin A. E. Sazonov O. S. Fyodorova I. A. Deyev Ye. E. Kremer |
author_sort |
L. M. Ogorodova |
title |
Opistorchis felineus invasion influence on immunity in bronchial asthma |
title_short |
Opistorchis felineus invasion influence on immunity in bronchial asthma |
title_full |
Opistorchis felineus invasion influence on immunity in bronchial asthma |
title_fullStr |
Opistorchis felineus invasion influence on immunity in bronchial asthma |
title_full_unstemmed |
Opistorchis felineus invasion influence on immunity in bronchial asthma |
title_sort |
opistorchis felineus invasion influence on immunity in bronchial asthma |
publisher |
Siberian State Medical University (Tomsk) |
series |
Bûlleten' Sibirskoj Mediciny |
issn |
1682-0363 1819-3684 |
publishDate |
2010-06-01 |
description |
To investigate the molecular mechanisms of human immune response modification by Opisthorchis felineus antigens in bronchial asthma. The experimental study was performed with cell cultures from patients with bronchial asthma, patients with opisthorchiasis, and patients with BA and opisthorchiasis co-occurred. A proposed down-regulation of immune response by higher level of IL10 and TGFB genes expression in patients with opisthorchiasis was revealed. |
topic |
opisthorchis felineus invasion bronchial asthma immunity gene expression |
url |
https://bulletin.tomsk.ru/jour/article/view/1601 |
work_keys_str_mv |
AT lmogorodova opistorchisfelineusinvasioninfluenceonimmunityinbronchialasthma AT mbfreidin opistorchisfelineusinvasioninfluenceonimmunityinbronchialasthma AT aesazonov opistorchisfelineusinvasioninfluenceonimmunityinbronchialasthma AT osfyodorova opistorchisfelineusinvasioninfluenceonimmunityinbronchialasthma AT iadeyev opistorchisfelineusinvasioninfluenceonimmunityinbronchialasthma AT yeekremer opistorchisfelineusinvasioninfluenceonimmunityinbronchialasthma |
_version_ |
1721253740168609792 |