Opistorchis felineus invasion influence on immunity in bronchial asthma

To investigate the molecular mechanisms of human immune response modification by Opisthorchis felineus antigens in bronchial asthma. The experimental study was performed with cell cultures from patients with bronchial asthma, patients with opisthorchiasis, and patients with BA and opisthorchiasis co...

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Main Authors: L. M. Ogorodova, M. B. Freidin, A. E. Sazonov, O. S. Fyodorova, I. A. Deyev, Ye. E. Kremer
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2010-06-01
Series:Bûlleten' Sibirskoj Mediciny
Subjects:
Online Access:https://bulletin.tomsk.ru/jour/article/view/1601
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spelling doaj-ca20301075cf4d46b232858a978dbd582021-07-29T08:37:52ZengSiberian State Medical University (Tomsk)Bûlleten' Sibirskoj Mediciny1682-03631819-36842010-06-0193859010.20538/1682-0363-2010-3-85-901104Opistorchis felineus invasion influence on immunity in bronchial asthmaL. M. Ogorodova0M. B. Freidin1A. E. Sazonov2O. S. Fyodorova3I. A. Deyev4Ye. E. Kremer5Сибирский государственный медицинский университетНИИ медицинской генетики СО РАМНСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетTo investigate the molecular mechanisms of human immune response modification by Opisthorchis felineus antigens in bronchial asthma. The experimental study was performed with cell cultures from patients with bronchial asthma, patients with opisthorchiasis, and patients with BA and opisthorchiasis co-occurred. A proposed down-regulation of immune response by higher level of IL10 and TGFB genes expression in patients with opisthorchiasis was revealed.https://bulletin.tomsk.ru/jour/article/view/1601opisthorchis felineus invasionbronchial asthmaimmunitygene expression
collection DOAJ
language English
format Article
sources DOAJ
author L. M. Ogorodova
M. B. Freidin
A. E. Sazonov
O. S. Fyodorova
I. A. Deyev
Ye. E. Kremer
spellingShingle L. M. Ogorodova
M. B. Freidin
A. E. Sazonov
O. S. Fyodorova
I. A. Deyev
Ye. E. Kremer
Opistorchis felineus invasion influence on immunity in bronchial asthma
Bûlleten' Sibirskoj Mediciny
opisthorchis felineus invasion
bronchial asthma
immunity
gene expression
author_facet L. M. Ogorodova
M. B. Freidin
A. E. Sazonov
O. S. Fyodorova
I. A. Deyev
Ye. E. Kremer
author_sort L. M. Ogorodova
title Opistorchis felineus invasion influence on immunity in bronchial asthma
title_short Opistorchis felineus invasion influence on immunity in bronchial asthma
title_full Opistorchis felineus invasion influence on immunity in bronchial asthma
title_fullStr Opistorchis felineus invasion influence on immunity in bronchial asthma
title_full_unstemmed Opistorchis felineus invasion influence on immunity in bronchial asthma
title_sort opistorchis felineus invasion influence on immunity in bronchial asthma
publisher Siberian State Medical University (Tomsk)
series Bûlleten' Sibirskoj Mediciny
issn 1682-0363
1819-3684
publishDate 2010-06-01
description To investigate the molecular mechanisms of human immune response modification by Opisthorchis felineus antigens in bronchial asthma. The experimental study was performed with cell cultures from patients with bronchial asthma, patients with opisthorchiasis, and patients with BA and opisthorchiasis co-occurred. A proposed down-regulation of immune response by higher level of IL10 and TGFB genes expression in patients with opisthorchiasis was revealed.
topic opisthorchis felineus invasion
bronchial asthma
immunity
gene expression
url https://bulletin.tomsk.ru/jour/article/view/1601
work_keys_str_mv AT lmogorodova opistorchisfelineusinvasioninfluenceonimmunityinbronchialasthma
AT mbfreidin opistorchisfelineusinvasioninfluenceonimmunityinbronchialasthma
AT aesazonov opistorchisfelineusinvasioninfluenceonimmunityinbronchialasthma
AT osfyodorova opistorchisfelineusinvasioninfluenceonimmunityinbronchialasthma
AT iadeyev opistorchisfelineusinvasioninfluenceonimmunityinbronchialasthma
AT yeekremer opistorchisfelineusinvasioninfluenceonimmunityinbronchialasthma
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