5-Acetyl-4-(2,5-dimethoxyphenyl)-6-methyl-1-(prop-2-ynyl)-3,4-dihydropyrimidin-2(1H)-one
In the title compound, C18H20N2O4, the 3,4-dihydropyrimidin-2(1H)-one ring has a screw-boat conformation. The mean plane through this heterocycle is almost perpendicular to the prop-2-ynyl chain and to the benzene ring, with which it makes a dihedral angle of 87.63 (6)°. The plane through the acetyl...
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International Union of Crystallography
2017-06-01
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| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S2414314617008161 |
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doaj-ca1feae791ce4077bdcb277e428e06162020-11-24T23:03:29ZengInternational Union of CrystallographyIUCrData2414-31462017-06-0126x17081610.1107/S2414314617008161su41545-Acetyl-4-(2,5-dimethoxyphenyl)-6-methyl-1-(prop-2-ynyl)-3,4-dihydropyrimidin-2(1H)-oneHanane Kaoukabi0Moha Taourirte1Mohamed El Azhari2Hassan B. Lazrek3Mohamed Saadi4Lahcen El Ammari5Laboratoire de Chimie Bio-organique et Macromoléculaire, Faculté des Sciences et Techniques Guéliz, Marrakech, MoroccoLaboratoire de Chimie Bio-organique et Macromoléculaire, Faculté des Sciences et Techniques Guéliz, Marrakech, MoroccoLaboratoire de la Matière Condensée et des Nanostructures, Faculté des Sciences et Techniques Guéliz, Marrakech, MoroccoLaboratoire de Chimie Biomoléculaire et Médicinale, Faculté des Sciences Semlalia, Marrakech, MoroccoLaboratoire de Chimie du Solide Appliquée, Faculty of Sciences, Mohammed V University in Rabat, Avenue Ibn Battouta, BP 1014, Rabat, MoroccoLaboratoire de Chimie du Solide Appliquée, Faculty of Sciences, Mohammed V University in Rabat, Avenue Ibn Battouta, BP 1014, Rabat, MoroccoIn the title compound, C18H20N2O4, the 3,4-dihydropyrimidin-2(1H)-one ring has a screw-boat conformation. The mean plane through this heterocycle is almost perpendicular to the prop-2-ynyl chain and to the benzene ring, with which it makes a dihedral angle of 87.63 (6)°. The plane through the acetyl group makes a dihedral angle of 33.11 (8)° with the mean plane of the heterocycle. There is an intramolecular C—H...O hydrogen bond present forming an S(6) ring motif. In the crystal, molecules are linked by C—H...O hydrogen bonds, forming layers parallel to the bc plane. There are also C—H...π interactions present within the layers.http://scripts.iucr.org/cgi-bin/paper?S2414314617008161crystal structuredihydropyrimidinoneC—H...O hydrogen bondsC—H...π interactions |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Hanane Kaoukabi Moha Taourirte Mohamed El Azhari Hassan B. Lazrek Mohamed Saadi Lahcen El Ammari |
| spellingShingle |
Hanane Kaoukabi Moha Taourirte Mohamed El Azhari Hassan B. Lazrek Mohamed Saadi Lahcen El Ammari 5-Acetyl-4-(2,5-dimethoxyphenyl)-6-methyl-1-(prop-2-ynyl)-3,4-dihydropyrimidin-2(1H)-one IUCrData crystal structure dihydropyrimidinone C—H...O hydrogen bonds C—H...π interactions |
| author_facet |
Hanane Kaoukabi Moha Taourirte Mohamed El Azhari Hassan B. Lazrek Mohamed Saadi Lahcen El Ammari |
| author_sort |
Hanane Kaoukabi |
| title |
5-Acetyl-4-(2,5-dimethoxyphenyl)-6-methyl-1-(prop-2-ynyl)-3,4-dihydropyrimidin-2(1H)-one |
| title_short |
5-Acetyl-4-(2,5-dimethoxyphenyl)-6-methyl-1-(prop-2-ynyl)-3,4-dihydropyrimidin-2(1H)-one |
| title_full |
5-Acetyl-4-(2,5-dimethoxyphenyl)-6-methyl-1-(prop-2-ynyl)-3,4-dihydropyrimidin-2(1H)-one |
| title_fullStr |
5-Acetyl-4-(2,5-dimethoxyphenyl)-6-methyl-1-(prop-2-ynyl)-3,4-dihydropyrimidin-2(1H)-one |
| title_full_unstemmed |
5-Acetyl-4-(2,5-dimethoxyphenyl)-6-methyl-1-(prop-2-ynyl)-3,4-dihydropyrimidin-2(1H)-one |
| title_sort |
5-acetyl-4-(2,5-dimethoxyphenyl)-6-methyl-1-(prop-2-ynyl)-3,4-dihydropyrimidin-2(1h)-one |
| publisher |
International Union of Crystallography |
| series |
IUCrData |
| issn |
2414-3146 |
| publishDate |
2017-06-01 |
| description |
In the title compound, C18H20N2O4, the 3,4-dihydropyrimidin-2(1H)-one ring has a screw-boat conformation. The mean plane through this heterocycle is almost perpendicular to the prop-2-ynyl chain and to the benzene ring, with which it makes a dihedral angle of 87.63 (6)°. The plane through the acetyl group makes a dihedral angle of 33.11 (8)° with the mean plane of the heterocycle. There is an intramolecular C—H...O hydrogen bond present forming an S(6) ring motif. In the crystal, molecules are linked by C—H...O hydrogen bonds, forming layers parallel to the bc plane. There are also C—H...π interactions present within the layers. |
| topic |
crystal structure dihydropyrimidinone C—H...O hydrogen bonds C—H...π interactions |
| url |
http://scripts.iucr.org/cgi-bin/paper?S2414314617008161 |
| work_keys_str_mv |
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| _version_ |
1725633677901168640 |