Group testing can improve the cost-efficiency of prospective-retrospective biomarker studies

Group testing can improve the cost-efficiency of prospective-retrospective biomarker studies

Abstract Background Cancer treatment is increasingly dependent on biomarkers for prognostication and treatment selection. Potential biomarkers are frequently evaluated in prospective-retrospective studies in which biomarkers are measured retrospectively on archived specimens after completion of pros...

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Bibliographic Details
Main Authors: Wei Zhang, Zhiwei Zhang, Julia Krushkal, Aiyi Liu
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Medical Research Methodology
Subjects:
Biomarker study design
Cost-efficiency
Group testing
Pooling
Two-phase sampling
Online Access:https://doi.org/10.1186/s12874-021-01239-4

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