Improved synthesis of quinocetone and its two desoxymetabolites

Oxidation of o-nitroaniline with sodium hypochlorite afforded benzofurazan oxide in 96 % yield, and treatment of benzofurazan oxide with acetylacetone in the presence of triethylamine gave 2-acetyl-3-methyl-quinoxaline- -1,4-dioxide in 94 % yield. Finally, condensation of 2-acetyl-3-methyl-quinoxali...

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Bibliographic Details
Main Authors: Li Yuwen, Qiu Mei, Bai Yubin, Qu Shaoqi, Hao Zhihui
Format: Article
Language:English
Published: Serbian Chemical Society 2018-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2018/0352-51391700118L.pdf