Involvement of cyclin-dependent kinase-like 2 in cognitive function required for contextual and spatial learning in mice

Involvement of cyclin-dependent kinase-like 2 in cognitive function required for contextual and spatial learning in mice

Cyclin-dependent kinase-like 2 (Cdkl2) is a cdc2-related serine/threonine protein kinase that is postnatally expressed in various brain regions, including the cerebral cortex, entorhinal cortex, hippocampus, amygdala, and dorsal thalamus. The extremely high Cdkl2 expression in these regions suggests...

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Bibliographic Details
Main Authors:	Hiroshi Gomi, Takayuki Sassa, Richard F Thomson, Shigeyoshi Itohara
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2010-04-01
Series:	Frontiers in Behavioral Neuroscience
Subjects:	Rett Syndrome Cognitive Function active avoidance cdc2-related kinase Cdkl2 contextual fear conditioning
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fnbeh.2010.00017/full

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